Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.40 |
| ▸ | ATXN2 | Q99700 | 4/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 2/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31586864 | 0.96 | ACACB (0.47) | ACACBCRBNDDB1ENPP2ATXN2 | |
| SCHEMBL30148829 | 0.95 | CRBN (0.42) | ACACBCRBNDDB1MLKLNR3C1 | |
| SCHEMBL24735127 | 0.91 | CRBN (0.47) | CRBNDDB1NR3C1PGRSLC6A4 | |
| SCHEMBL30158207 | 0.91 | CRBN (0.47) | CRBNDDB1NR3C1PGRSLC6A4 | |
| SCHEMBL30612355 | 0.88 | MEN1 (0.51) | CRBNDDB1NR3C1PGRSLC6A4 | |
| SCHEMBL29190407 | 0.88 | CRBN (0.45) | CRBNDDB1NR3C1PGRSLC6A4 | |
| SCHEMBL24735228 | 0.88 | MEN1 (0.51) | CRBNDDB1NR3C1PGRSLC6A4 | |
| SCHEMBL23121080 | 0.87 | JAK1 (0.39) | ACACBCRBNDDB1NR3C1PGR | |
| SCHEMBL29607702 | 0.87 | JAK1 (0.39) | ACACBCRBNDDB1NR3C1PGR | |
| SCHEMBL25267641 | 0.86 | CRBN (0.40) | CRBNDDB1PARP1MLKLNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754858-A | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111936498-B | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-04-16 | — | — | CN | disclosed |