Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234130 | 0.72 | RAD52 (0.56) | AKR1B10AKR1B1RAD52TSHRKMT2A | |
| SCHEMBL3165711 | 0.69 | KMT2A (0.50) | AKR1B10AKR1B1KMT2AALDH1A1KDM4E | |
| SCHEMBL21685452 | 0.68 | TSHR (0.41) | AKR1B10AKR1B1TSHRKMT2AL3MBTL1 | |
| SCHEMBL21685619 | 0.67 | ALDH1A1 (0.47) | AKR1B10AKR1B1TSHRPOLBALDH1A1 | |
| SCHEMBL7604837 | 0.67 | TSHR (0.43) | TSHRPOLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL4592116 | 0.65 | MAPT (0.49) | POLBKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12875609 | 0.64 | KMT2A (0.56) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27757531 | 0.63 | ALDH1A1 (0.48) | POLBKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1590530 | 0.63 | GAA (0.56) | RAD52TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL2875153 | 0.63 | KMT2A (0.50) | AKR1B10AKR1B1TSHRKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813297-A | Phenyl and pyridopyrazole derivatives as DDR1 inhibitors | 莱德克斯制药公共有限公司 | 2024-04-02 | — | — | CN | disclosed |