SCHEMBL30874407

SCHEMBL30874407

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 6/20 0.58
▸ IL1RN P18510 5/20 0.54
▸ GHSR Q92847 4/20 0.54
▸ ERAP1 Q9NZ08 4/20 0.54
▸ ECE1 P42892 5/20 0.54
▸ KISS1R Q969F8 1/20 0.53
▸ NPBWR1 P48145 1/20 0.52
▸ CTSB P07858 1/20 0.51
▸ CTSK P43235 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496496 0.95 GHSR (0.56) GHSRECE1
SCHEMBL29378588 0.95 ERAP2 (0.63) ERAP2IL1RNGHSRERAP1ECE1
SCHEMBL31583852 0.95 ERAP2 (0.63) ERAP2IL1RNGHSRERAP1ECE1
SCHEMBL30929767 0.94 ERAP2 (0.58) ERAP2IL1RNGHSRERAP1ECE1
SCHEMBL30929763 0.94 ERAP2 (0.58) ERAP2IL1RNGHSRERAP1ECE1
SCHEMBL30093048 0.94 GHSR (0.60) GHSRECE1
SCHEMBL30093069 0.94 EDNRA (0.59) ERAP2IL1RNGHSRERAP1ECE1
SCHEMBL29684075 0.94 ERAP2 (0.58) ERAP2IL1RNGHSRERAP1ECE1
SCHEMBL30130563 0.93 GHSR (0.59) GHSRECE1
SCHEMBL30130571 0.93 GHSR (0.59) GHSRECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES Nanjing Finepeptide Biopharmaceutical Co.,Ltd (CN) 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES GLP1R, IAPP, GCG ERAP2 912/4885IL1RN 1890/4885GHSR 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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