Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 13/20 | 0.39 |
| ▸ | HTR7 | P34969 | 13/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874919 | 0.74 | DPP4 (0.45) | DPP4HTR1AHTR7VNN1 | |
| SCHEMBL30874925 | 0.74 | HTR1A (0.41) | DPP4HTR1AHTR7 | |
| SCHEMBL26832953 | 0.74 | TACR1 (0.40) | — | |
| SCHEMBL26837043 | 0.74 | TACR1 (0.46) | — | |
| SCHEMBL26841467 | 0.73 | TACR1 (0.42) | — | |
| SCHEMBL24665999 | 0.73 | LTK (0.54) | LTKALKDYRK1BCHEK1DAPK3 | |
| SCHEMBL30874956 | 0.70 | HTR1A (0.46) | DPP4HTR1AHTR7 | |
| SCHEMBL16496604 | 0.70 | HTR1A (0.43) | DPP4HTR1AHTR7 | |
| SCHEMBL30874842 | 0.70 | PREP (0.46) | DPP4VNN1 | |
| SCHEMBL2177077 | 0.69 | DPP4 (0.57) | DPP4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |