Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ALPP | P05187 | 1/20 | 0.45 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341408 | 0.77 | PARG (0.54) | TP53LMNATSHRHTTDPP4 | |
| SCHEMBL5252741 | 0.75 | LMNA (0.60) | ALDH1A1LMNATSHRHTTALPL | |
| SCHEMBL13571388 | 0.74 | HPGD (0.46) | LMNADPP4 | |
| SCHEMBL3587930 | 0.71 | KDM4E (0.69) | ALDH1A1LMNATSHRHTTALPL | |
| SCHEMBL30874846 | 0.71 | DPP4 (0.47) | DPP4 | |
| SCHEMBL30874923 | 0.71 | DPP4 (0.44) | DPP4 | |
| SCHEMBL30874926 | 0.71 | DPP4 (0.44) | DPP4GAA | |
| SCHEMBL30874830 | 0.70 | DPP4 (0.43) | DPP4 | |
| SCHEMBL30874870 | 0.70 | DPP4 (0.45) | DPP4 | |
| SCHEMBL474918 | 0.69 | DPP4 (0.57) | ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |