Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | CFD | P00746 | 11/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29230807 | 0.89 | CFD (0.33) | CFDFAP | |
| SCHEMBL24664591 | 0.89 | CFD (0.33) | CFDFAP | |
| SCHEMBL29230804 | 0.89 | CFD (0.33) | CFDFAP | |
| SCHEMBL30341409 | 0.78 | DPP4 (0.41) | — | |
| SCHEMBL30874871 | 0.76 | PIK3CA (0.34) | CFDPIK3CA | |
| SCHEMBL30874841 | 0.74 | CFD (0.35) | CFDPIK3CA | |
| SCHEMBL24666276 | 0.74 | CFD (0.38) | CFD | |
| SCHEMBL24666217 | 0.74 | CFD (0.38) | CFD | |
| SCHEMBL24665428 | 0.74 | CFD (0.38) | CFD | |
| SCHEMBL30874921 | 0.73 | CNR2 (0.34) | CNR2CFDPIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |