Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 15/20 | 0.61 |
| ▸ | INSR | P06213 | 7/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL25950554 | 0.89 | ALK (0.60) | ALKINSRBTKMAP4K1 | |
| SCHEMBL30183975 | 0.85 | MAP4K1 (0.62) | ALKINSRMAP4K1 | |
| SCHEMBL25337779 | 0.85 | MAP4K1 (0.62) | ALKINSRMAP4K1 | |
| SCHEMBL30875675 | 0.85 | MAP4K1 (0.65) | ALKMAP4K1MET | |
| Hydrochloric Acid SCHEMBL29172302 | 0.84 | MAP4K1 (0.64) | ALKMAP4K1MET | |
| SCHEMBL20231589 | 0.80 | ALK (0.71) | ALKINSRBTKMAP4K1MET | |
| SCHEMBL25947559 | 0.78 | ALK (0.57) | ALKINSRMAP4K1MET | |
| SCHEMBL20214436 | 0.78 | MAP4K1 (0.77) | ALKINSRMAP4K1 | |
| SCHEMBL20214556 | 0.78 | MAP4K1 (0.77) | ALKINSRMAP4K1 | |
| SCHEMBL29805906 | 0.78 | MAP4K1 (0.77) | ALKINSRMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |