Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.71 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717840 | 0.86 | PNMT (0.81) | PNMTADRA2ATDP2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1947220 | 0.85 | PNMT (0.78) | PNMTADRA2ATDP2ADRA2BADRA2C | |
| SCHEMBL29382023 | 0.83 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL324460 | 0.83 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL325622 | 0.82 | PNMT (0.97) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29651180 | 0.82 | PNMT (0.97) | PNMTADRA2AADRA2BADRA2C | |
| Nitric Acid SCHEMBL521643 | 0.82 | PNMT (0.73) | PNMTADRA2ATDP2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL27698594 | 0.82 | PNMT (0.97) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1269277 | 0.80 | PNMT (0.87) | PNMTADRA2ATDP2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL10004303 | 0.79 | PNMT (0.84) | PNMTADRA2ATDP2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |