Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106917 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL29384229 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL3087607 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL10621114 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL30905102 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL24323603 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL31106850 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL30178287 | 1.00 | MME (0.46) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL3145911 | 0.92 | SMN1; SMN2 (0.50) | MMEACECPA1ACE2SMN1; SMN2 | |
| SCHEMBL783990 | 0.92 | SMN1; SMN2 (0.50) | MMEACECPA1ACE2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790025-B2 | External gradient chromatofocusing | CRYOBIOPHYSICA, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20070144973-A1 | External gradient chromatofocusing | CRYOBIOPHYSICA, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| EP-1628729-A2 | EXTERNAL GRADIENT CHROMATOFOCUSING | Cryobiophysica, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004103519-A2 | EXTERNAL GRADIENT CHROMATOFOCUSING | CRYOBIOPHYSICA, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
| US-4334972-A | OF CHROMATOGRAPHY OR ELECTROPHORESIS | PHARMACIA FINE CHEMICALS AB (SE) | 1982-06-15 | — | — | US | disclosed |