SCHEMBL29384229

SCHEMBL29384229

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nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.46
ACE P12821 1/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.40
FAAH O00519 2/20 0.39
LTA4H P09960 4/20 0.39
ANPEP P15144 1/20 0.39
ECE1 P42892 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31106917 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL3087602 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL3087607 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL10621114 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL30905102 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL24323603 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL31106850 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL30178287 1.00 MME (0.46) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL3145911 0.92 SMN1; SMN2 (0.50) MMEACECPA1ACE2SMN1; SMN2
SCHEMBL783990 0.92 SMN1; SMN2 (0.50) MMEACECPA1ACE2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270258-A1 BICYCLIC PEPTIDYL INHIBITORS OHIO STATE INNOVATION FOUNDATION 2025-08-28 US claimed
US-12281181-B2 Bicyclic peptidyl inhibitors OHIO STATE INNOVATION FOUNDATION (US) 2025-04-22 US claimed
WO-2025034601-A1 AAV GENE THERAPY FOR ALPHA-1 ANTITRYPSIN DEFICIENCY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-02-13 WO claimed
US-20240392304-A1 CIRCULAR RNA AND PREPARATION METHOD THEREOF CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) 2024-11-28 US claimed
WO-2024233366-A2 MODIFIED CAS9-IID NUCLEASES AND USES THEREOF Aera Therapeutics, Inc. (US) 2024-11-14 WO claimed
WO-2024206825-A2 MODIFIED ISCB NUCLEASES, MODIFIED GUIDE RNAS, AND USES THEREOF Aera Therapeutics, Inc. (US) 2024-10-03 WO claimed
US-20240263173-A1 HIGH-THROUGHPUT PRECISION GENOME EDITING IN HUMAN CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-08-08 US claimed
EP-4405480-A1 CIRCULAR RNA AND PREPARATION METHOD THEREOF Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) 2024-07-31 EP claimed
EP-4384616-A2 HIGH-THROUGHPUT PRECISION GENOME EDITING IN HUMAN CELLS The Board of Trustees of the Leland Stanford Junior University (US) 2024-06-19 EP claimed
CN-117625631-A Zebra fish nxhl marker gene and application thereof 广西壮族自治区人民医院 2024-03-01 CN claimed
US-20230349001-A1 BIOMOLECULAR CHARACTERISTIC IDENTIFICATION METHOD AND SYSTEM THEREOF FOR TAIWAN TILAPIA STRAINS NATIONAL TAIWAN OCEAN UNIVERSITY (TW) 2023-11-02 US claimed
US-20230322859-A1 BICYCLIC PEPTIDYL INHIBITORS OHIO STATE INNOVATION FOUNDATION 2023-10-12 US claimed
US-11673919-B2 Bicyclic peptidyl inhibitors OHIO STATE INNOVATION FOUNDATION (US) 2023-06-13 US claimed
WO-2023046153-A1 CIRCULAR RNA AND PREPARATION METHOD THEREOF CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) 2023-03-30 WO claimed
WO-2023019164-A2 HIGH-THROUGHPUT PRECISION GENOME EDITING IN HUMAN CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-02-16 WO claimed
US-20220281920-A1 BICYCLIC PEPTIDYL INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-09-08 US claimed
US-11339192-B2 Bicyclic peptidyl inhibitors OHIO STATE INNOVATION FOUNDATION (US) 2022-05-24 US claimed
US-20260132463-A1 METHODS OF ENRICHING TARGETED NUCLEIC ACID, IDENTIFYING OFF-TARGET AND EVALUATING GENE EDITING EFFICIENCY GENEDITBIO LTD (CN) 2026-05-14 US disclosed
CN-114047330-A Turn-on doxycycline specificity homogeneous phase detection system based on FRET and application thereof 北京维德维康生物技术有限公司 2022-02-15 CN disclosed
CN-106661580-B Antisense oligonucleotides for treating pompe disease 鹿特丹伊拉斯谟大学医疗中心 2022-02-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281920-A1 BICYCLIC PEPTIDYL INHIBITORS NFKBIA, IKBKG, NFRKB MME 3591/4885ACE 4664/4885CPA1 2173/4885
US-11673919-B2 Bicyclic peptidyl inhibitors NFKBIA, IKBKG, NFRKB MME 3591/4885ACE 4664/4885CPA1 2173/4885
US-20230322859-A1 BICYCLIC PEPTIDYL INHIBITORS NFKBIA, IKBKG, NFRKB MME 3591/4885ACE 4664/4885CPA1 2173/4885
US-12281181-B2 Bicyclic peptidyl inhibitors NFKBIA, IKBKG, NFRKB MME 3591/4885ACE 4664/4885CPA1 2173/4885
US-20250270258-A1 BICYCLIC PEPTIDYL INHIBITORS NFKBIA, IKBKG, NFRKB MME 3591/4885ACE 4664/4885CPA1 2173/4885
US-20260132463-A1 METHODS OF ENRICHING TARGETED NUCLEIC ACID, IDENTIFYING OFF-TARGET AND EVALUATING GENE EDITING EFFICIENCY ADAR, ADA, RNGTT MME 3777/4885ACE 3218/4885CPA1 1352/4885
US-11339192-B2 Bicyclic peptidyl inhibitors NFKBIA, IKBKG, NFRKB MME 3591/4885ACE 4664/4885CPA1 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.