Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.45 |
| ▸ | KDR | P35968 | 9/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.42 |
| ▸ | JAK3 | P52333 | 6/20 | 0.42 |
| ▸ | TEK | Q02763 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660638 | 1.00 | LCK (0.45) | LCKKDRKITSRCBACE1 | |
| SCHEMBL20660512 | 0.83 | ALDH1A1 (0.43) | LCKKDRKITSRCBACE1 | |
| SCHEMBL20660563 | 0.82 | LCK (0.43) | LCKKDRKITSRCMAPK14 | |
| SCHEMBL30116105 | 0.82 | LCK (0.43) | LCKKDRKITSRCMAPK14 | |
| SCHEMBL20671018 | 0.82 | ALDH1A1 (0.46) | LCKKDRBACE1MAPK14JAK3 | |
| SCHEMBL21626139 | 0.82 | BACE1 (0.50) | LCKKDRKITSRCBACE1 | |
| SCHEMBL20660414 | 0.80 | CYP1A2 (0.41) | LCKKDRKITSRCABL1 | |
| SCHEMBL20660507 | 0.80 | ALDH1A1 (0.40) | LCKKDRKITSRCMAPK14 | |
| SCHEMBL20660522 | 0.79 | BACE1 (0.54) | LCKKDRKITSRCBACE1 | |
| SCHEMBL20660457 | 0.78 | PIK3CA (0.47) | LCKKDRMAPK14JAK3TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |