Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514465 | 1.00 | ENPP2 (0.44) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL28831875 | 0.88 | GLA (0.44) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL28319373 | 0.83 | ENPP2 (0.41) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL104898 | 0.83 | GLA (0.46) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL4083138 | 0.82 | ENPP2 (0.47) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL23056923 | 0.79 | GLA (0.44) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL1719895 | 0.79 | GLA (0.44) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL6706801 | 0.79 | S1PR1 (0.46) | ENPP2GLAS1PR1ADRA1DADRA1A | |
| SCHEMBL22435570 | 0.79 | GLA (0.44) | ENPP2TSHRGLAGSK3BS1PR1 | |
| SCHEMBL320196 | 0.79 | ENPP2 (0.46) | ENPP2GLAGSK3BS1PR1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |