SCHEMBL30876236

SCHEMBL30876236

NC(=O)C1[C@H]2CC(F)(F)C[C@@H]12

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488096 1.00 APLNR (0.33) APLNR
SCHEMBL15105952 0.77 GRM2 (0.36) APLNR
SCHEMBL15105950 0.77 GRM2 (0.36) APLNR
SCHEMBL7210725 0.77 GRM2 (0.36) APLNR
SCHEMBL16407797 0.77 GRM2 (0.36) APLNR
SCHEMBL15114438 0.77 GRM2 (0.36) APLNR
SCHEMBL15116881 0.77 GRM2 (0.36) APLNR
SCHEMBL15116472 0.75 APLNR (0.33) APLNR
SCHEMBL15540967 0.74
SCHEMBL15113298 0.71 APLNR (0.31) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005606-A TEAD inhibitors 武汉人福创新药物研发中心有限公司 2024-05-10 CN disclosed