Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30876222 | 1.00 | AXL (0.39) | AXLTYRO3MERTKMAPTJAK3 | |
| SCHEMBL29206953 | 1.00 | AXL (0.39) | AXLTYRO3MERTKMAPTJAK3 | |
| SCHEMBL29206956 | 1.00 | AXL (0.39) | AXLTYRO3MERTKMAPTJAK3 | |
| SCHEMBL29206983 | 0.92 | TEAD1 (0.37) | MAPTCDK1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL30876242 | 0.92 | TEAD1 (0.37) | MAPTCDK1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL29206985 | 0.92 | TEAD1 (0.37) | MAPTCDK1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL30876215 | 0.92 | TEAD1 (0.37) | MAPTCDK1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL30876254 | 0.84 | NAMPT (0.37) | AXLTYRO3MERTKKDM4E | |
| SCHEMBL30876291 | 0.84 | NAMPT (0.37) | AXLTYRO3MERTKKDM4E | |
| SCHEMBL29206982 | 0.84 | NAMPT (0.37) | AXLTYRO3MERTKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |