Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206982 | 1.00 | NAMPT (0.37) | NAMPTGALR2KDM4EAURKARPS6KB1 | |
| SCHEMBL29206979 | 1.00 | NAMPT (0.37) | NAMPTGALR2KDM4EAURKARPS6KB1 | |
| SCHEMBL30876254 | 1.00 | NAMPT (0.37) | NAMPTGALR2KDM4EAURKARPS6KB1 | |
| SCHEMBL30876288 | 0.93 | PAX8 (0.38) | PAX8 | |
| SCHEMBL29206994 | 0.93 | PAX8 (0.38) | PAX8 | |
| SCHEMBL30876259 | 0.93 | PAX8 (0.38) | PAX8 | |
| SCHEMBL30876258 | 0.93 | PAX8 (0.38) | PAX8 | |
| SCHEMBL29206998 | 0.93 | PAX8 (0.38) | PAX8 | |
| SCHEMBL30876222 | 0.84 | AXL (0.39) | KDM4EAXLTYRO3MERTK | |
| SCHEMBL30876240 | 0.84 | AXL (0.39) | KDM4EAXLTYRO3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |