SCHEMBL30876370

SCHEMBL30876370

COc1ccc(N2C(=O)CSC2c2ccc(F)cc2)c(C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 19/20 1.00
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
GFER P55789 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19306464 1.00 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL19317334 0.91 HTR7 (0.83) HTR7MEN1KMT2AGFER
SCHEMBL19306026 0.91 HTR7 (0.83) HTR7MEN1KMT2AGFER
SCHEMBL30876437 0.91 HTR7 (0.83) HTR7MEN1KMT2AGFER
SCHEMBL19306061 0.88 HTR7 (1.00) HTR7MEN1KMT2AGFER
SCHEMBL30876451 0.88 HTR7 (1.00) HTR7
SCHEMBL19305943 0.88 HTR7 (1.00) HTR7
SCHEMBL19354534 0.86 HTR7 (0.75) HTR7
SCHEMBL19306235 0.85 HTR7 (1.00) HTR7
SCHEMBL19306343 0.85 HTR7 (1.00) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3426246-B1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RES INST (TW) 2024-05-01 EP disclosed