SCHEMBL30876408

SCHEMBL30876408

COc1ccccc1N1C(=O)CSC1c1cccc(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 12/20 1.00
CYP3A4 P08684 1/20 0.78
CYP2C19 P33261 1/20 0.78
ALDH1A1 P00352 1/20 0.72
KMT2A Q03164 1/20 0.67
GFER P55789 1/20 0.65
HDAC1 Q13547 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19306499 1.00 HTR7 (1.00) HTR7CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL19306213 0.93 HTR7 (1.00) HTR7CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL19306337 0.88 HTR7 (1.00) HTR7KMT2AGFER
SCHEMBL30876421 0.88 HTR7 (1.00) HTR7KMT2AGFER
SCHEMBL19317329 0.84 HTR7 (0.82) HTR7CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL19306288 0.83 HTR7 (0.84) HTR7CYP3A4CYP2C19
SCHEMBL19306374 0.82 HTR7 (1.00) HTR7CYP3A4CYP2C19ALDH1A1GFER
SCHEMBL19306248 0.82 HTR7 (1.00) HTR7KMT2AGFER
SCHEMBL11056998 0.81 HTR7 (0.69) HTR7CYP3A4CYP2C19ALDH1A1GFER
SCHEMBL19306119 0.81 HTR7 (1.00) HTR7CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3426246-B1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RES INST (TW) 2024-05-01 EP disclosed