Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292103 | 0.85 | RAB9A (0.61) | RAB9AMAPTNPSR1NOS1NOS2 | |
| SCHEMBL8361615 | 0.85 | MAPK1 (0.56) | RAB9ANPC1TDP1APPMAOB | |
| SCHEMBL7539917 | 0.83 | RAB9A (0.60) | RAB9AMAPTNPSR1NPC1TDP1 | |
| SCHEMBL3938617 | 0.83 | MAOB (0.52) | RAB9AMAPTNPSR1NPC1TDP1 | |
| SCHEMBL30150593 | 0.82 | RAB9A (0.62) | RAB9AMAPTNPSR1NOS1NOS2 | |
| SCHEMBL1323646 | 0.82 | RAB9A (0.62) | RAB9AMAPTNPSR1NOS1NOS2 | |
| SCHEMBL24932986 | 0.81 | RAB9A (0.61) | RAB9AMAPTNPSR1NPC1APP | |
| SCHEMBL9791457 | 0.81 | MAPT (0.61) | RAB9AMAPTNPSR1APPNOS1 | |
| SCHEMBL7154078 | 0.81 | RAB9A (0.61) | RAB9AMAPTNPSR1NPC1APP | |
| SCHEMBL30896277 | 0.81 | RAB9A (0.61) | RAB9AMAPTNPSR1NPC1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957231-A | Fused ring compound, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-04-30 | — | — | CN | disclosed |