SCHEMBL30877006

SCHEMBL30877006

CCC(c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)P(=O)(O)O.CCOP(=O)(O)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 5/20 0.53
NR1I2 O75469 1/20 0.44
GAA P10253 5/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
ALDH1A1 P00352 5/20 0.36
TSHR P16473 4/20 0.36
MAPK1 P28482 3/20 0.36
CYP1A2 P05177 3/20 0.36
CYP3A4 P08684 3/20 0.36
MAPT P10636 3/20 0.36
BLM P54132 2/20 0.36
ATM Q13315 2/20 0.36
HIF1A Q16665 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
USP2 O75604 1/20 0.36
CYP2D6 P10635 1/20 0.36
LMNA P02545 3/20 0.35
RECQL P46063 1/20 0.35
CYP2C9 P11712 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45804 0.87 HMGCR (0.62) HMGCRNR1I2GAAKMT2AMEN1
Calcium SCHEMBL30510960 0.86 HMGCR (0.61) HMGCRNR1I2GAAKMT2AMEN1
SCHEMBL28422669 0.86 HMGCR (0.61) HMGCRNR1I2GAAKMT2AMEN1
SCHEMBL7156553 0.86 HMGCR (0.61) HMGCRNR1I2GAAKMT2AMEN1
Potassium SCHEMBL4892236 0.86 HMGCR (0.61) HMGCRNR1I2GAAKMT2AMEN1
SCHEMBL225937 0.86 HMGCR (0.61) HMGCRNR1I2GAAKMT2AMEN1
SCHEMBL4689967 0.85 HMGCR (0.46) HMGCRNR1I2GAAKMT2AMEN1
Calcium SCHEMBL7116377 0.84 HMGCR (0.44) HMGCRNR1I2GAAKMT2AMEN1
SCHEMBL340446 0.84 HMGCR (0.44) HMGCRNR1I2GAAKMT2AMEN1
SCHEMBL15051658 0.77 HMGCR (0.54) HMGCRNR1I2GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024090855-A1 ISOCYANATE COMPOSITION 한화솔루션 주식회사 2024-05-02 WO disclosed