SCHEMBL4689967

SCHEMBL4689967

CCC(c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 4/20 0.46
LMNA P02545 3/20 0.45
RECQL P46063 1/20 0.45
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.42
NR1I2 O75469 1/20 0.42
ALDH1A1 P00352 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
GAA P10253 3/20 0.41
CYP1A2 P05177 5/20 0.40
TSHR P16473 4/20 0.40
CYP3A4 P08684 3/20 0.40
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 2/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Calcium SCHEMBL7116377 0.98 HMGCR (0.44) HMGCRLMNARECQLCA2CA1
SCHEMBL340446 0.98 HMGCR (0.44) HMGCRLMNARECQLCA2CA1
SCHEMBL5670221 0.90 HMGCR (0.46) HMGCRLMNARECQLCA2CA1
SCHEMBL5486244 0.87 HMGCR (0.43) HMGCRLMNARECQLCA2CA1
SCHEMBL30877006 0.85 HMGCR (0.53) HMGCRLMNARECQLNR1I2ALDH1A1
SCHEMBL563208 0.84 HMGCR (0.43) HMGCRLMNARECQLCA2CA1
SCHEMBL916917 0.84 HMGCR (0.43) HMGCRLMNARECQLCA2CA1
Potassium Ion SCHEMBL5912033 0.84 HMGCR (0.43) HMGCRLMNARECQLCA2CA1
SCHEMBL915240 0.84 HMGCR (0.43) HMGCRLMNARECQLCA2CA1
Zinc Ion SCHEMBL915462 0.84 HMGCR (0.43) HMGCRLMNARECQLCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4225503-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-08-16 EP claimed
EP-3122819-B1 MELT POLYMERIZATION POLYCARBONATE QUENCHING TECHNICAL FIELD SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-07-19 EP claimed
EP-2534202-B1 POLYMER COMPOSITION MITSUBISHI CHEMICAL EUROPE GMBH (DE) 2022-04-27 EP claimed
US-20220106488-A1 Grinding Aid for Titanium Dioxide Particles KRONOS INTERNATIONAL INC. (DE) 2022-04-07 US claimed
EP-0366305-B1 Stabilized polyethylene composition BP CHEM INT LTD (GB) 1994-05-18 EP claimed
EP-0269570-A2 Compositions stabilized with N-hydroxyiminodiacetic or dipropionic acids or esters thereof CIBA-GEIGY AG (CH) 1988-06-01 EP claimed
US-12122898-B2 Polyolefin resin composition and molded article using same ADEKA CORPORATION (JP) 2024-10-22 US disclosed
US-11884809-B2 Molded article and laminate incorporating acrylic resin composition ADEKA CORPORATION (JP) 2024-01-30 US disclosed
US-20230416535-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-12-28 US disclosed
EP-3527617-B1 POLYOLEFIN RESIN COMPOSITION AND MOLDED ARTICLE USING SAME ADEKA CORP (JP) 2023-11-29 EP disclosed
EP-4225503-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-08-16 EP disclosed
EP-3560999-B1 POLYAMIDE RESIN COMPOSITION FOR HOSE, AND HOSE OBTAINED BY USING POLYAMIDE RESIN COMPOSITION BRIDGESTONE CORP (JP) 2023-08-16 EP disclosed
EP-3122819-B1 MELT POLYMERIZATION POLYCARBONATE QUENCHING TECHNICAL FIELD SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-07-19 EP disclosed
EP-0095571-B1 POLYHYDRIC ALCOHOL ETHERS OF 2,2,6,6-TETRAMETHYL-4-PIPERIDONE KETALS AND SYNTHETIC RESIN COMPOSITIONS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-09-23 EP disclosed
US-4263434-A UV STABILIZERS FOR POLYMERS CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1981-04-21 US disclosed
US-4148747-A FOR POLYMERS RAYCHEM CORPORATION (US) 1979-04-10 US disclosed
US-4108829-A PHOTOSTABILITY CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1978-08-22 US disclosed
US-4086207-A REACTING A DIAMINE WITH CARBONYL CHLORIDE OR A DIISOCYANATE CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1978-04-25 US disclosed
US-4086204-A LIGHT STABILIZERS CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1978-04-25 US disclosed
US-4052279-A HYDROXY AROMATIC COMPOUND CONTAINING SULFUR AND AN ORGANIC PHOSPHONATE AS POLYMER ANTIOXIDANT RAYCHEM CORPORATION (US) 1977-10-04 US disclosed