Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29285160 | 1.00 | AXL (0.39) | AXLPRKCIDYRK1AALDH1A1KDM4E | |
| SCHEMBL23270478 | 0.83 | AXL (0.41) | AXLPRKCIDYRK1AALDH1A1KDM4E | |
| SCHEMBL29478937 | 0.83 | AXL (0.41) | AXLPRKCIDYRK1AALDH1A1KDM4E | |
| SCHEMBL31636611 | 0.70 | KDM4E (0.56) | ALDH1A1KDM4EHPGDRXFP1ADORA2A | |
| SCHEMBL3521028 | 0.70 | KDM4E (0.56) | ALDH1A1KDM4EHPGDRXFP1ADORA2A | |
| SCHEMBL2399491 | 0.69 | AXL (0.33) | AXLPRKCI | |
| SCHEMBL1016847 | 0.68 | DYRK1A (0.46) | AXLPRKCIDYRK1AADORA2AHTT | |
| SCHEMBL9921699 | 0.68 | PRKCI (0.42) | AXLPRKCIALDH1A1KDM4ETTBK1 | |
| SCHEMBL23647524 | 0.68 | PRKCI (0.38) | AXLPRKCIDYRK1AALDH1A1KDM4E | |
| SCHEMBL12563109 | 0.67 | PRKCI (0.49) | AXLPRKCIALDH1A1KDM4ETTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |