Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29285183 | 1.00 | FABP6 (0.42) | FABP6ERN1ALDH1A1GAAHSD17B10 | |
| SCHEMBL31513053 | 0.77 | ALDH1A1 (0.41) | ERN1ALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL30954167 | 0.75 | FABP6 (0.41) | FABP6ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL23832869 | 0.75 | FABP6 (0.41) | FABP6ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL23532996 | 0.75 | KDM4E (0.38) | FABP6ERN1ALDH1A1GAAHSD17B10 | |
| SCHEMBL23846769 | 0.72 | FABP6 (0.40) | FABP6ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL30056728 | 0.72 | FABP6 (0.40) | FABP6ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL15332907 | 0.72 | ALDH1A1 (0.33) | FABP6ALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL29285169 | 0.72 | ERN1 (0.37) | ERN1ALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL29285141 | 0.71 | ERN1 (0.39) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |