Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | APOL1 | O14791 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206503 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAGPR84SMN1; SMN2HTR1D | |
| SCHEMBL30877835 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAGPR84SMN1; SMN2HTR1D | |
| SCHEMBL29206548 | 0.89 | SMN1; SMN2 (0.38) | ALDH1A1LMNASMN1; SMN2HTR1D | |
| SCHEMBL30053401 | 0.86 | MEN1 (0.38) | ALDH1A1LMNAHTR1DPOLBTDP1 | |
| SCHEMBL29206488 | 0.85 | AR (0.34) | SMN1; SMN2HTR1D | |
| SCHEMBL29206539 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAGPR84SMN1; SMN2HTR1D | |
| SCHEMBL30877820 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAGPR84SMN1; SMN2HTR1D | |
| SCHEMBL29206559 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL24243785 | 0.81 | HTR2A (0.50) | ALDH1A1 | |
| SCHEMBL31077708 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAGPR84APOL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |