Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.47 |
| ▸ | WNT1 | P04628 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643731 | 1.00 | DYRK1A (0.47) | DYRK1AWNT1GSK3BMAPK1MAPT | |
| SCHEMBL30878061 | 0.80 | HASPIN (0.45) | DYRK1AWNT1MAPK1MAPTCLK2 | |
| SCHEMBL30878068 | 0.80 | CREBBP (0.42) | DYRK1AWNT1MAPK1MAPTCLK2 | |
| SCHEMBL19643357 | 0.80 | CREBBP (0.42) | DYRK1AWNT1MAPK1MAPTCLK2 | |
| SCHEMBL19643702 | 0.80 | HASPIN (0.45) | DYRK1AWNT1MAPK1MAPTCLK2 | |
| SCHEMBL30956731 | 0.79 | SLC22A12 (0.50) | DYRK1AGSK3BMAPK1MAPTSLC22A12 | |
| SCHEMBL14953387 | 0.79 | SLC22A12 (0.50) | DYRK1AGSK3BMAPK1MAPTSLC22A12 | |
| SCHEMBL31478764 | 0.76 | DYRK1A (0.56) | DYRK1AWNT1GSK3BMAPTCLK2 | |
| SCHEMBL31501389 | 0.76 | DYRK1A (0.62) | DYRK1AWNT1GSK3BMAPTCLK2 | |
| SCHEMBL25602112 | 0.76 | DYRK1A (0.62) | DYRK1AWNT1GSK3BMAPTCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112165944-B | Imidazopiperazine inhibitors of transcriptional activator proteins | 德州大学系统董事会 | 2024-04-09 | — | — | CN | disclosed |