Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639541 | 0.90 | ATM (0.51) | ATMCYP3A4CTSSCTSLCTSB | |
| SCHEMBL27032968 | 0.90 | ATM (0.51) | ATMCYP3A4CTSSCTSLCTSB | |
| SCHEMBL27137035 | 0.90 | ATM (0.51) | ATMCYP3A4CTSSCTSLCTSB | |
| SCHEMBL29828736 | 0.89 | CTSS (0.49) | ATMSYKCYP3A4CTSSCTSL | |
| SCHEMBL30790785 | 0.87 | ATM (0.43) | ATMSYKCYP3A4CTRB1MAPT | |
| SCHEMBL30639500 | 0.82 | ATM (0.43) | ATMSYKCYP3A4CTRB1MAPT | |
| SCHEMBL29097022 | 0.82 | ATM (0.43) | ATMSYKCYP3A4CTRB1MAPT | |
| SCHEMBL29096900 | 0.82 | ATM (0.43) | ATMSYKCYP3A4CTRB1MAPT | |
| SCHEMBL29096903 | 0.82 | ATM (0.43) | ATMSYKCYP3A4CTRB1MAPT | |
| SCHEMBL29828719 | 0.82 | ATM (0.43) | ATMSYKCYP3A4CTRB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587012-A1 | COMBINATION OF MACROCYCLIC CFTR MODULATORS WITH CFTR CORRECTORS AND / OR CFTR POTENTIATORS | Idorsia Pharmaceuticals Ltd (CH) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024056791-A1 | COMBINATION OF MACROCYCLIC CFTR MODULATORS WITH CFTR CORRECTORS AND / OR CFTR POTENTIATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-03-21 | — | — | WO | disclosed |