Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 7/20 | 0.69 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.60 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.60 |
| ▸ | SRC | P12931 | 6/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | PAK4 | O96013 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879194 | 0.89 | WEE1 (0.62) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878325 | 0.88 | WEE1 (0.58) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878382 | 0.87 | WEE1 (0.70) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878465 | 0.85 | WEE1 (0.77) | WEE1FGFR1SRCEGFRFGFR2 | |
| SCHEMBL30879020 | 0.83 | WEE1 (0.56) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878417 | 0.83 | WEE1 (0.54) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878454 | 0.81 | FGFR1 (0.51) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878289 | 0.80 | CDK4 (0.59) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878366 | 0.80 | FGFR1 (0.66) | WEE1FGFR1RIPK2NOD2ACVR1 | |
| SCHEMBL30878380 | 0.80 | WEE1 (0.48) | WEE1FGFR1SRCPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | claimed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | claimed |
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |