Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 7/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.47 |
| ▸ | EGFR | P00533 | 6/20 | 0.46 |
| ▸ | SRC | P12931 | 5/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | STAT5A | P42229 | 1/20 | 0.46 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30878665 | 0.90 | WEE1 (0.49) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL30878325 | 0.88 | WEE1 (0.58) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL30878331 | 0.83 | WEE1 (0.69) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL30878465 | 0.81 | WEE1 (0.77) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL30878380 | 0.80 | WEE1 (0.48) | WEE1FGFR1EGFRSRCPDGFRB | |
| SCHEMBL30879020 | 0.80 | WEE1 (0.56) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL20674164 | 0.80 | WEE1 (0.46) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL30878444 | 0.80 | FGFR1 (0.49) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL30878400 | 0.80 | FGFR1 (0.53) | WEE1FGFR1EGFRSRCACVR1 | |
| SCHEMBL30878436 | 0.80 | EGFR (0.49) | WEE1FGFR1EGFRSRCTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | claimed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | claimed |
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |