Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 20/20 | 0.66 |
| ▸ | WDR48 | Q8TAF3 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295953 | 0.93 | USP1 (0.67) | USP1WDR48 | |
| SCHEMBL30696482 | 0.90 | USP1 (0.71) | USP1WDR48 | |
| SCHEMBL27174428 | 0.90 | USP1 (0.71) | USP1WDR48 | |
| SCHEMBL29295747 | 0.89 | USP1 (0.61) | USP1WDR48 | |
| SCHEMBL30878538 | 0.88 | USP1 (0.64) | USP1WDR48 | |
| SCHEMBL30878418 | 0.87 | USP1 (0.67) | USP1WDR48 | |
| SCHEMBL29296077 | 0.86 | USP1 (0.67) | USP1WDR48 | |
| SCHEMBL30033977 | 0.85 | USP1 (0.66) | USP1WDR48 | |
| SCHEMBL27088174 | 0.85 | USP1 (0.66) | USP1WDR48 | |
| SCHEMBL25344956 | 0.85 | USP1 (0.71) | USP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980294-A | Ubiquitin-specific protease 1 (USP 1) inhibitors | 海南先声再明医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |