Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 7/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33532809 | 0.88 | ESR1 (0.41) | ESR1ESR2KMT2AGPR119MTNR1B | |
| SCHEMBL30878596 | 0.84 | PDK2 (0.48) | ESR1ESR2MTNR1BGHSR | |
| SCHEMBL30878562 | 0.78 | ESR1 (0.57) | ESR1ESR2KMT2AMTNR1BPARP1 | |
| SCHEMBL25722286 | 0.78 | ESR1 (0.57) | ESR1ESR2KMT2AMTNR1BPARP1 | |
| SCHEMBL30878583 | 0.77 | CA12 (0.47) | ESR1ESR2GHSR | |
| SCHEMBL30878565 | 0.74 | CA12 (0.48) | ESR1ESR2GHSR | |
| SCHEMBL30878534 | 0.72 | ESR1 (0.58) | ESR1ESR2KMT2AMTNR1B | |
| SCHEMBL22145358 | 0.71 | ESR1 (0.45) | ESR1ESR2KMT2AMTNR1BNR1H2 | |
| SCHEMBL30878560 | 0.71 | ESR1 (0.53) | ESR1ESR2KMT2AMTNR1B | |
| SCHEMBL33533519 | 0.70 | MEN1 (0.42) | ESR2KMT2AGPR119NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587126-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | Amphista Therapeutics Ltd (GB) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024057021-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-03-21 | — | — | WO | disclosed |