Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 12/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30878565 | 0.95 | CA12 (0.48) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL30878596 | 0.93 | PDK2 (0.48) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL33530437 | 0.82 | DRD2 (0.46) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL30878634 | 0.81 | SCN9A (0.44) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL30878525 | 0.78 | ESR1 (0.57) | CA12CA1CA2CA9ESR1 | |
| SCHEMBL3079418 | 0.78 | GHSR (0.54) | CA12CA1CA2CA9GHSR | |
| SCHEMBL33532809 | 0.77 | ESR1 (0.41) | ESR1ESR2GHSR | |
| SCHEMBL33532346 | 0.77 | CA1 (0.51) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL33532142 | 0.77 | DRD2 (0.51) | CA12CA1CA2CA9 | |
| SCHEMBL30878631 | 0.77 | ESR1 (0.40) | ESR1ESR2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587126-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | Amphista Therapeutics Ltd (GB) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024057021-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-03-21 | — | — | WO | disclosed |