Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 18/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970582 | 0.89 | WDR5 (0.67) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL15961410 | 0.89 | WDR5 (0.67) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL30879000 | 0.86 | WDR5 (0.73) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL282334 | 0.86 | WDR5 (0.73) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL30878705 | 0.86 | WDR5 (0.64) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL30879141 | 0.85 | WDR5 (0.61) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL30879355 | 0.83 | WDR5 (0.62) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL16096147 | 0.82 | WDR5 (0.67) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL20213949 | 0.81 | WDR5 (1.00) | WDR5GAAALDH1A1CYP2D6HTT | |
| SCHEMBL30879250 | 0.80 | TSHR (0.56) | WDR5GAAALDH1A1CYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |