SCHEMBL3087900

SCHEMBL3087900

NCc1ncccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30461478 1.00
Hydrochloric Acid SCHEMBL26910346 0.98 ALDH1A1 (0.40)
Bromide SCHEMBL20767138 0.98 ALDH1A1 (0.38)
Hydrochloric Acid SCHEMBL657974 0.98 ALDH1A1 (0.40)
Bromide SCHEMBL20767137 0.96 ALDH1A1 (0.36)
SCHEMBL4431518 0.84 PRMT5 (0.41)
SCHEMBL507581 0.79
SCHEMBL30201085 0.79
SCHEMBL11100271 0.78 HRH1 (0.49)
SCHEMBL10041246 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4681712-A2 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-01-21 EP disclosed
EP-4126854-B1 PROCESS FOR THE PRODUCTION OF FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-12-03 EP disclosed
EP-4615439-A2 SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS AND THEIR APPLICATIONS Humanwell Pharmaceutical US, Inc. (US) 2025-09-17 EP disclosed
EP-4499628-A1 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERIVATIVES AS DEGRONS IN PROTACS GlaxoSmithKline Intellectual Property Development Limited (GB) 2025-02-05 EP disclosed
US-20240174693-A1 SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS AND THEIR APPLICATIONS YICHANG HUMANWELL PHARMACEUTICALS CO., LTD. (CN) 2024-05-30 US disclosed
WO-2024102754-A2 SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS AND THEIR APPLICATIONS HUMANWELL PHARMACUETICAL US, INC. (US) 2024-05-16 WO disclosed
WO-2023180388-A1 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERIVATIVES AS DEGRONS IN PROTACS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-09-28 WO disclosed
US-20230212159-A1 Process for the Production of Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2023-07-06 US disclosed
US-20230212159-A1 Process for the Production of Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2023-07-06 US disclosed
WO-2023107870-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KINNATE BIOPHARMA INC. (US) 2023-06-15 WO disclosed
US-11040033-B2 Therapeutic heterocyclic compounds GILEAD SCIENCES, INC. (US) 2021-06-22 US disclosed
EP-3509627-A1 LYSINE SPECIFIC HISTONE DEMETHYLASE-1 INHIBITORS AND USES THEREFOR University of Canberra (AU) 2019-07-17 EP disclosed
WO-2019040102-A1 THERAPEUTIC HETEROCYCLIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2019-02-28 WO disclosed
WO-2018045422-A1 LYSINE SPECIFIC HISTONE DEMETHYLASE-1 INHIBITORS AND USES THEREFOR UNIVERSITY OF CANBERRA (AU) 2018-03-15 WO disclosed
EP-2118101-B1 IMIDAZO [1,5-A] PYRIDINE DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE PROBIODRUG AG (DE) 2012-09-26 EP disclosed
US-7803810-B2 Inhibitors PROBIODRUG AG (DE) 2010-09-28 US disclosed
EP-2118101-A1 IMIDAZO [1,5-A] PYRIDINE DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE Probiodrug AG (DE) 2009-11-18 EP disclosed
US-20080234313-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2008-09-25 US disclosed
WO-2008110523-A1 IMIDAZO [1,5-A] PYRIDINE DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE PROBIODRUG AG (DE) 2008-09-18 WO disclosed
CN-101239978-A Imidazopyridines compounds UNIV SOUTHERN MEDICAL (CN) 2008-08-13 CN disclosed