Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033756 | 1.00 | MEN1 (0.62) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL1446664 | 0.84 | LMNA (0.62) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29888811 | 0.84 | LMNA (0.62) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL2644891 | 0.84 | LMNA (0.62) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29527091 | 0.83 | LMNA (0.69) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4029870 | 0.83 | PDE7A (0.73) | MEN1KMT2AMAPTLMNAPDE7A | |
| SCHEMBL5565241 | 0.83 | HTT (0.60) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL2031919 | 0.82 | PDE7A (0.60) | MEN1KMT2AMAPTLMNAPDE7A | |
| SCHEMBL8395820 | 0.82 | LMNA (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL2028774 | 0.81 | LMNA (0.62) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980309-A | Tricyclic fused pyrimidine compounds useful as HER2 inhibitors | 百时美施贵宝公司 | 2024-05-03 | — | — | CN | disclosed |