SCHEMBL30879458

CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)CC)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC(=N)N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	1/20	0.47

▸	ENPEP	Q07075	5/20	0.47

▸	RXFP1	Q9HBX9	1/20	0.47

▸	VIPR2	P41587	6/20	0.47

▸	VIPR1	P32241	4/20	0.47

▸	TASP1	Q9H6P5	1/20	0.46

▸	ECE1	P42892	1/20	0.44

▸	GLP1R	P43220	1/20	0.44

▸	MUS81	Q96NY9	1/20	0.44

▸	NPY4R	P50391	4/20	0.44

▸	NPY1R	P25929	3/20	0.44

▸	NPY2R	P49146	3/20	0.44

▸	NPY5R	Q15761	3/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30483972	0.98	ENPEP (0.49)	BACE1ENPEPRXFP1VIPR2VIPR1
SCHEMBL30879453	0.95	NPY4R (0.48)	BACE1ENPEPRXFP1VIPR2VIPR1
SCHEMBL30483984	0.95	RXFP1 (0.46)	BACE1ENPEPRXFP1VIPR2VIPR1
SCHEMBL30912040	0.94	RXFP1 (0.50)	BACE1ENPEPRXFP1VIPR2VIPR1
SCHEMBL30912039	0.94	RXFP1 (0.50)	BACE1ENPEPRXFP1VIPR2VIPR1
SCHEMBL30912047	0.94	RXFP1 (0.49)	BACE1ENPEPRXFP1VIPR2VIPR1
SCHEMBL30912045	0.90	NPY4R (0.49)	RXFP1VIPR2VIPR1NPY4RNPY1R
SCHEMBL30912041	0.89	RXFP1 (0.48)	BACE1RXFP1VIPR2VIPR1TASP1
SCHEMBL30912048	0.89	RXFP1 (0.50)	BACE1RXFP1VIPR2VIPR1NPY4R
SCHEMBL31318575	0.89	VIPR1 (0.53)	BACE1RXFP1VIPR2VIPR1TASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240181015-A1	EFFECT OF GHRH ANTAGONISTS IN DIABETES AND OBESITY	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US)	2024-06-06	—	—	US	disclosed