SCHEMBL30879595

SCHEMBL30879595

COc1ccc2ccoc2c1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.51
CYP3A4 P08684 4/20 0.51
MAOA P21397 3/20 0.51
CYP2D6 P10635 2/20 0.51
TSHR P16473 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP2A6 P11509 1/20 0.51
ACHE P22303 1/20 0.51
PDE4A P27815 1/20 0.51
MAPK1 P28482 1/20 0.51
SLC6A3 Q01959 1/20 0.51
CYP2A13 Q16696 1/20 0.51
KDM4E B2RXH2 9/20 0.46
ALDH1A1 P00352 8/20 0.46
HPGD P15428 7/20 0.46
LMNA P02545 4/20 0.46
HSD17B10 Q99714 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27499528 1.00 CYP1A2 (0.51) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL31207186 0.83 CYP3A4 (0.41) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL4363589 0.79 PDE4B (0.46) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL5987900 0.78 HTR2A (0.42) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL30659689 0.78 CYP3A4 (0.42) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL10158521 0.78 CYP3A4 (0.42) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL30973555 0.78 CYP3A4 (0.50) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL14010908 0.78 CYP1A2 (0.43) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL20615145 0.76 CYP3A4 (0.51) CYP1A2CYP3A4MAOACYP2D6TSHR
SCHEMBL20615328 0.74 CYP3A4 (0.46) CYP1A2CYP3A4MAOACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118320030-A Compound preparation for treating children dyspepsia and adult stomach diseases and preparation method thereof 王金祥 2024-07-12 CN claimed
CN-117843407-A Disease and pest resistant fertilizer produced by traditional Chinese medicine and preparation process thereof 宝鸡子奕生物科技有限公司 2024-04-09 CN disclosed