Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879595 | 0.83 | CYP1A2 (0.51) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL27499528 | 0.83 | CYP1A2 (0.51) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL31207185 | 0.77 | MAOA (0.33) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL28512047 | 0.77 | MCL1 (0.39) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL4363589 | 0.71 | PDE4B (0.46) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL30659689 | 0.70 | CYP3A4 (0.42) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL10158521 | 0.70 | CYP3A4 (0.42) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL5987900 | 0.70 | HTR2A (0.42) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL28684298 | 0.70 | MAPT (0.55) | CYP3A4CYP1A2CYP2C19MAPK1KDM4E | |
| SCHEMBL5233122 | 0.69 | MAPT (0.41) | CYP3A4CYP1A2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222712-A1 | IMIDAZOPYRIDINE OR IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2024-10-31 | — | — | WO | disclosed |