Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24001003 | 0.82 | MDM2 (0.52) | GAAKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL31270898 | 0.81 | LSS (0.45) | RAB9ANAMPTKDM4E | |
| SCHEMBL10662756 | 0.81 | GAA (0.45) | GAAKMT2AMEN1MAPTALDH1A1 | |
| Imidazole-1-Carboxylic Acid Phenylamide SCHEMBL10668282 | 0.81 | RAB9A (0.50) | SMN1; SMN2GAATP53QPCTNPC1 | |
| SCHEMBL10662282 | 0.80 | KMT2A (0.53) | GAAKMT2AMEN1QPCTNPC1 | |
| SCHEMBL31402684 | 0.78 | TSHR (0.51) | KMT2ATP53MEN1MAPTNPC1 | |
| SCHEMBL21843382 | 0.78 | HTT (0.58) | SMN1; SMN2GAAKMT2AMEN1MAPT | |
| SCHEMBL18184936 | 0.76 | CYP19A1 (0.56) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL4173548 | 0.75 | QPCT (0.56) | GAAKMT2AESR2QPCTMAPT | |
| SCHEMBL24000883 | 0.74 | RAB9A (0.53) | SMN1; SMN2KMT2ATP53MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092222-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |