Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL8059326 | 1.00 | LMNA (0.67) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL8020399 | 1.00 | LMNA (0.67) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL30613971 | 1.00 | LMNA (0.67) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL29390618 | 1.00 | LMNA (0.67) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL869140 | 1.00 | — | — | |
| Acrylic Acid SCHEMBL8021956 | 1.00 | LMNA (0.67) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL27583561 | 1.00 | LMNA (0.67) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL5964862 | 0.97 | LMNA (0.62) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL28945554 | 0.97 | — | — | |
| Acrylic Acid SCHEMBL28586715 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024117094-A1 | PHOTOCURABLE RESIN COMPOSITION, OPTICAL COMPONENT, METHOD FOR PRODUCING OPTICAL COMPONENT, LIGHT EMITTING DEVICE, AND METHOD FOR PRODUCING LIGHT EMITTING DEVICE | パナソニックＩＰマネジメント株式会社 | 2024-06-06 | — | — | WO | disclosed |