Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880261 | 0.78 | ACACB (0.51) | CYP2C9CYP2C19CYP19A1ACACBACACA | |
| SCHEMBL23588190 | 0.76 | ACACB (0.50) | CYP2C9CYP2C19CYP19A1ACACBACACA | |
| SCHEMBL26027547 | 0.68 | ACACB (0.61) | CYP2C9CYP2C19CYP19A1ACACBACACA | |
| SCHEMBL6954855 | 0.67 | CYP2D6 (0.56) | CYP2C9CYP2C19CYP19A1NPC1RAB9A | |
| SCHEMBL35210439 | 0.67 | S1PR1 (0.67) | ACACBACACAS1PR1S1PR3NPC1 | |
| SCHEMBL13926721 | 0.65 | S1PR1 (0.69) | ACACBACACAS1PR1S1PR3NPC1 | |
| SCHEMBL12270837 | 0.64 | S1PR1 (0.64) | CYP2C9CYP2C19CYP19A1ACACBACACA | |
| SCHEMBL27897965 | 0.64 | HDAC4 (0.56) | CYP2C9CYP2C19CYP19A1ACACBACACA | |
| SCHEMBL14257518 | 0.64 | RAB9A (0.66) | CYP2C9CYP2C19CYP19A1NPC1RAB9A | |
| SCHEMBL12243191 | 0.64 | S1PR1 (0.59) | ACACBACACAS1PR1S1PR3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089421-A1 | TETRAZOLE DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2024-05-02 | — | — | WO | disclosed |