Mukonine

Mukonine

SCHEMBL30880286

COC(=O)c1cc(OC)c2[nH]c3c(C(C)=O)cccc3c2c1.COC(=O)c1cc(OC)c2[nH]c3ccccc3c2c1

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 1/20 0.59
KIF11 P52732 1/20 0.48
PIM1 P11309 1/20 0.47
PIM3 Q86V86 1/20 0.47
MPL P40238 1/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30880280 0.93 GAA (0.47) FTOKIF11PIM1PIM3MAPT
Mukonine SCHEMBL17817163 0.89 FTO (0.73) FTOKIF11PIM1PIM3MPL
Mukonine SCHEMBL30880285 0.89 FTO (0.73) FTOKIF11PIM1PIM3MPL
SCHEMBL4779330 0.82 GAA (0.59) FTOKIF11MAPTKDM4EALDH1A1
SCHEMBL30880282 0.80 PIM1 (0.43) FTOKIF11PIM1PIM3MAPT
SCHEMBL159997 0.78 PBRM1 (0.57) KIF11PIM1PIM3MPLMAPT
Mukoeic Acid SCHEMBL29460309 0.77 FTO (0.56) FTOKIF11PIM1PIM3MAPT
SCHEMBL9485757 0.77 MPL (0.61) FTOKIF11PIM1PIM3MPL
SCHEMBL5327857 0.75 GAA (0.56) FTOKIF11MAPTKDM4EALDH1A1
Clausine E SCHEMBL30915067 0.75 FTO (1.00) FTOKIF11PIM1PIM3MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602029-A1 NOVEL THERAPEUTIC MOLECULE Pillai Universal LLC (US) 2025-08-20 EP disclosed
WO-2024079677-A1 NOVEL THERAPEUTIC MOLECULE PILLAI UNIVERSAL LLC (US) 2024-04-18 WO disclosed