Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 12/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 5/20 | 0.47 |
| ▸ | COQ8A | Q8NI60 | 5/20 | 0.47 |
| ▸ | NLK | Q9UBE8 | 5/20 | 0.47 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.47 |
| ▸ | STK16 | O75716 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880564 | 0.92 | GAK (0.57) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880458 | 0.91 | GAK (0.58) | GAKALKRIPK2COQ8ANLK | |
| SCHEMBL30880617 | 0.89 | GAK (0.58) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880581 | 0.88 | GAK (0.57) | GAKRIPK2COQ8ANLKCGAS | |
| SCHEMBL30880666 | 0.86 | HTT (0.60) | GAKRIPK2COQ8ANLKEGFR | |
| SCHEMBL30880661 | 0.85 | EGFR (0.59) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880519 | 0.85 | GAK (0.59) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880635 | 0.85 | GAK (0.56) | GAKALKRIPK2COQ8ANLK | |
| SCHEMBL30880707 | 0.84 | GAK (0.58) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL30880457 | 0.83 | GAK (0.47) | GAKRIPK2COQ8ANLKEPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |