Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GAK | O14976 | 6/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.55 |
| ▸ | COQ8A | Q8NI60 | 3/20 | 0.55 |
| ▸ | NLK | Q9UBE8 | 3/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880707 | 0.89 | GAK (0.58) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880458 | 0.89 | GAK (0.58) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880722 | 0.88 | RIPK2 (0.49) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880531 | 0.87 | GAK (0.58) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880617 | 0.87 | GAK (0.58) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880628 | 0.86 | GAK (0.57) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880499 | 0.86 | GAK (0.57) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880737 | 0.86 | GAK (0.57) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880564 | 0.86 | GAK (0.57) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL30880581 | 0.86 | GAK (0.57) | GAKRIPK2COQ8ANLKADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |