Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552046 | 1.00 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BMAPK1EGLN1 | |
| SCHEMBL21730352 | 0.86 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BMAPK1CFTR | |
| SCHEMBL29906676 | 0.86 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BMAPK1CFTR | |
| SCHEMBL21730221 | 0.84 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL29906693 | 0.84 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAPK1 | |
| SCHEMBL21722507 | 0.83 | ADORA2A (0.72) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551964 | 0.81 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BEGLN1 | |
| SCHEMBL29907652 | 0.81 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BEGLN1 | |
| SCHEMBL22552058 | 0.77 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29907792 | 0.77 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |