Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730306 | 1.00 | KMT2A (0.51) | KMT2AMEN1ADORA2AADORA1TLR7 | |
| SCHEMBL21730308 | 0.85 | ADORA2A (0.55) | KMT2AMEN1ADORA2AADORA1TLR7 | |
| SCHEMBL29907717 | 0.85 | ADORA2A (0.55) | KMT2AMEN1ADORA2AADORA1TLR7 | |
| SCHEMBL22551908 | 0.81 | ADORA2A (0.48) | KMT2AADORA2AADORA1ADORA2B | |
| SCHEMBL30880775 | 0.81 | ADORA2A (0.48) | KMT2AADORA2AADORA1ADORA2B | |
| SCHEMBL22551993 | 0.78 | ADORA2A (0.57) | KMT2AADORA2AADORA1ADORA2B | |
| SCHEMBL30880823 | 0.78 | ADORA2A (0.57) | KMT2AADORA2AADORA1ADORA2B | |
| SCHEMBL29907746 | 0.76 | ADORA2A (0.57) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22552016 | 0.76 | ADORA2A (0.57) | ADORA2AADORA1ADORA2B | |
| SCHEMBL27877038 | 0.74 | KMT2A (0.68) | KMT2AMEN1HTTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |