Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 6/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.36 |
| ▸ | MYLK | Q15746 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881662 | 0.84 | RPS6KB1 (0.38) | RPS6KB1MAP2K4MAP2K7MAPK10MAPK14 | |
| SCHEMBL30881741 | 0.84 | KDR (0.40) | RPS6KB1MAP2K4KMT2AMAPK10MAPK14 | |
| SCHEMBL30881816 | 0.82 | PDK2 (0.37) | RPS6KB1MAP2K4MAPK10MAPK14PRKD3 | |
| SCHEMBL30881767 | 0.82 | RPS6KB1 (0.36) | GRM2RPS6KB1MAP2K4MAP2K7MAPK10 | |
| SCHEMBL30881810 | 0.80 | HPGD (0.36) | MAP2K4BTKMAPK1MAPK6 | |
| SCHEMBL30881772 | 0.76 | SCN9A (0.36) | RPS6KB1BTKIKBKB | |
| SCHEMBL30881768 | 0.74 | IKBKB (0.37) | BTKIKBKB | |
| SCHEMBL30881813 | 0.73 | BTK (0.37) | BTK | |
| SCHEMBL30881889 | 0.71 | IKBKB (0.38) | RPS6KB1MAP2K4MAPKAPK2BTKIKBKB | |
| SCHEMBL30881673 | 0.70 | NTRK1 (0.34) | GRM2RPS6KB1MAP2K4MAPKAPK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |