Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 5/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ACVR2B | Q13705 | 1/20 | 0.34 |
| ▸ | MYLK | Q15746 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881768 | 0.88 | IKBKB (0.37) | IKBKBJAK2RBP4CAMKK2BTK | |
| SCHEMBL30881889 | 0.85 | IKBKB (0.38) | IKBKBRPS6KB1MAP2K4JAK2RBP4 | |
| SCHEMBL30881772 | 0.85 | SCN9A (0.36) | IKBKBRPS6KB1JAK2RBP4BTK | |
| SCHEMBL30881752 | 0.82 | CHEK1 (0.43) | IKBKBRPS6KB1MAP2K4PRKD3MAPK9 | |
| SCHEMBL30881813 | 0.81 | BTK (0.37) | JAK2BTKCCNT1CDK9 | |
| SCHEMBL30881810 | 0.81 | HPGD (0.36) | MAP2K4JAK2BTKCCNT1CDK9 | |
| SCHEMBL30881921 | 0.80 | PDK2 (0.35) | PDK2PDK4IKBKBRPS6KB1RORC | |
| SCHEMBL30881662 | 0.80 | RPS6KB1 (0.38) | RPS6KB1MAP2K4JAK2PRKD3MAPK9 | |
| SCHEMBL30881741 | 0.80 | KDR (0.40) | RPS6KB1MAP2K4JAK2PRKD3MAPK9 | |
| SCHEMBL30881775 | 0.79 | SSTR4 (0.38) | IKBKBRPS6KB1RORCCAMKK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |