Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 4/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881673 | 0.84 | NTRK1 (0.34) | BTKMKNK1MKNK2CCNT1CDK9 | |
| SCHEMBL30881884 | 0.84 | BTK (0.33) | IRAK4BTKROCK1CCNT1CDK9 | |
| SCHEMBL30881670 | 0.84 | FGFR4 (0.33) | BTKCCNT1CDK9JAK2NTRK1 | |
| SCHEMBL30881767 | 0.83 | RPS6KB1 (0.36) | BTKROCK1CCNT1CDK9JAK2 | |
| SCHEMBL30881727 | 0.83 | CCNT1 (0.35) | ROCK2ROCK1CCNT1CDK9NTRK1 | |
| SCHEMBL30881702 | 0.82 | IRAK4 (0.32) | IRAK4BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881698 | 0.82 | NTRK1 (0.34) | IRAK4BTKROCK2JAK2NTRK1 | |
| SCHEMBL30881886 | 0.80 | JAK2 (0.34) | IRAK4BTKROCK2JAK2NTRK1 | |
| SCHEMBL30881768 | 0.78 | IKBKB (0.37) | CAMKK2BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881813 | 0.75 | BTK (0.37) | BTKCCNT1CDK9JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |