Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 3/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881884 | 0.85 | BTK (0.33) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30881673 | 0.85 | NTRK1 (0.34) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30881767 | 0.84 | RPS6KB1 (0.36) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30881765 | 0.84 | IRAK4 (0.34) | BTKNTRK1JAK2CCNT1CDK9 | |
| SCHEMBL30881727 | 0.83 | CCNT1 (0.35) | FGFR4NTRK1CCNT1CDK9 | |
| SCHEMBL30881698 | 0.83 | NTRK1 (0.34) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30881702 | 0.83 | IRAK4 (0.32) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30881886 | 0.81 | JAK2 (0.34) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30881809 | 0.75 | NTRK1 (0.35) | BTKNTRK1JAK2JAK1TYK2 | |
| SCHEMBL30900887 | 0.73 | HTT (0.46) | NTRK1JAK3CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |