Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209725 | 1.00 | ESR1 (0.35) | ESR1ESR2ARKCNN4 | |
| SCHEMBL30900876 | 0.80 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL22954098 | 0.79 | ESR1 (0.39) | ESR1ESR2AR | |
| SCHEMBL30881834 | 0.79 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL30881677 | 0.79 | KCNN4 (0.33) | ARKCNN4 | |
| SCHEMBL29209812 | 0.79 | KCNN4 (0.33) | ARKCNN4 | |
| SCHEMBL4403722 | 0.78 | CYP3A4 (0.47) | ESR1ESR2AR | |
| SCHEMBL23850353 | 0.77 | AR (0.46) | ESR1ESR2AR | |
| SCHEMBL4406925 | 0.74 | AR (0.39) | ESR1ESR2AR | |
| SCHEMBL3532342 | 0.72 | CYP2D6 (0.40) | ARKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |