Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881834 | 0.80 | KCNN4 (0.31) | KCNN4CYP11B1CYP11B2 | |
| SCHEMBL29209725 | 0.80 | ESR1 (0.35) | KCNN4 | |
| SCHEMBL30881677 | 0.80 | KCNN4 (0.33) | KCNN4CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL29209812 | 0.80 | KCNN4 (0.33) | KCNN4CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL30881822 | 0.80 | ESR1 (0.35) | KCNN4 | |
| SCHEMBL3532342 | 0.73 | CYP2D6 (0.40) | KCNN4EPAS1SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL30881806 | 0.72 | KCNN4 (0.43) | KCNN4SLC22A12KMT2A | |
| SCHEMBL29209695 | 0.72 | KCNN4 (0.43) | KCNN4SLC22A12KMT2A | |
| SCHEMBL21596788 | 0.71 | TRPV4 (0.48) | EPAS1MEN1PKMKMT2A | |
| SCHEMBL3530578 | 0.70 | FFAR1 (0.43) | KCNN4EPAS1SLC22A12CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |